EasyModel - protein modeling based on MODELLER

EasyModel

EasyModel: A User-Friendly Web-Based Interface Based on MODELLER

In this interface, we use the homology modeling method. The basis of prediction by homologous modeling is that the protein sequence is similar to one or more proteins with a known structure.

Advanced Modeling - Multiple Templates

Model a sequence with high identity to multiple templates.

Build a model using information from multiple templates, provide an alignment between all of the templates and your target sequence and list all of the templates in the knowns argument.

Advanced Modeling - Loop Refining

The loop optimization relies on a scoring function and optimization schedule adapted for loop modeling.

Select any set of atoms of your choosing model and generating a number of loop models.

Basic Modeling

Model a sequence with high identity to a template.

This section use a simple case where the template selection and target-template alignments are not a problem. This means that there is no gap between the amino acids.

How to cite

To cite EasyModel, in addition to the references related to MODELLER (see salilab.org/modeller), please reference:

Arab, S. S. & Dantism, A. EasyModel: a user-friendly web-based interface based on MODELLER. Scientific Reports 13, 17185 (2023). nature.com/articles/s41598-023-44505-9

Homology models on this server are built with MODELLER 10.8.